PubMed İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://acikerisim2.beykoz.edu.tr/handle/20.500.12879/5

Browse

Now showing 1 - 20 of 40

Binary Particle Swarm Optimization as a Detection Tool for Influential Subsets in Linear Regression
(Taylor & Francis Ltd, 2021) Deliorman, G.; Inan, D.
An influential observation is any point that has a huge effect on the coefficients of a regression line fitting the data. The presence of such observations in the data set reduces the sensitivity and validity of the statistical analysis. In the literature there are many methods used for identifying influential observations. However, many of those methods are highly influenced by masking and swamping effects and require distributional assumptions. Especially in the presence of influential subsets most of these methods are insufficient to detect these observations. This study aims to develop a new diagnostic tool for identifying influential observations using the meta-heuristic binary particle swarm optimization algorithm. This proposed approach does not require any distributional assumptions and also not affected by masking and swamping effects as the known methods. The performance of the proposed method is analyzed via simulations and real data set applications.
Case Report: Physiological and Psychological Underpinnings of Muscle Dysmorphia Using EEG, GSR, and Eye-Tracking
(Frontiers Media SA, 2025) Cinaroglu, Metin; Ulker, Selami Varol; Yilmazer, Eda; Sayar, Goekben Hizli
Background Muscle dysmorphia (MD), a subtype of Body Dysmorphic Disorder (BDD), involves an obsessive preoccupation with perceived insufficient muscularity despite an objectively muscular physique. While its psychological features are well-documented, physiological and attentional underpinnings remain underexplored.Objective This exploratory, proof-of-concept case series examines the psychological, physiological, and attentional characteristics of individuals with varying experiences of MD using a multimodal approach combining electroencephalography (EEG), galvanic skin response (GSR), and eye-tracking technologies.Methods Three male participants were purposefully selected to represent distinct clinical profiles: one with active MD and steroid use, one in sustained remission from MD, and one with no MD history. Participants completed validated psychological scales (MDDI, BIDQ, STAI, RSES) and were exposed to personalized visual stimuli (past, current, and idealized body images). A triangulated recording protocol was used to capture EEG, GSR, and eye-tracking data during stimulus exposure.Results Participants with current and past MD showed elevated beta wave activity, increased skin conductance, and attentional biases toward muscular regions, corresponding with higher self-reported distress and anxiety. In contrast, the control participant exhibited stable physiological responses and emotionally neutral reactions. Triangulated data revealed coherent patterns across subjective and physiological domains, supporting the internal validity of the findings despite the small sample.Conclusion These findings illustrate the potential of multimodal assessment in identifying candidate psychophysiological markers of MD. While not generalizable, this case-series provides a valuable framework for future hypothesis-driven research and supports the need for gender-specific diagnostic and intervention strategies in muscle dysmorphia.
Cognitive Behavioral Therapy for Muscle Dysmorphia and Anabolic Steroid-Related Psychopathology: A Randomized Controlled Trial
(MDPI, 2025) Cinaroglu, Metin; Yilmazer, Eda; Ulker, Selami Varol; Sayar, Gokben Hizli
Background/Objectives: Muscle dysmorphia (MD), a subtype of body dysmorphic disorder, is prevalent among males who engage in the non-medical use of anabolic-androgenic steroids (AASs) and performance-enhancing drugs (PEDs). These individuals often experience severe psychopathology, including mood instability, compulsivity, and a distorted body image. Despite its clinical severity, no randomized controlled trials (RCTs) have evaluated structured psychological treatments in this subgroup. This study aimed to assess the efficacy of a manualized cognitive behavioral therapy (CBT) protocol in reducing MD symptoms and associated psychological distress among male steroid users. Results: Participants in the CBT group showed significant reductions in MD symptoms from the baseline to post-treatment (MDDI: p < 0.001, d = 1.12), with gains sustained at follow-up. Large effect sizes were also observed in secondary outcomes including depressive symptoms (PHQ-9: d = 0.98), psychological distress (K10: d = 0.93), disordered eating (EDE-Q: d = 0.74), and exercise addiction (EAI: d = 1.07). No significant changes were observed in the control group. Significant group x time interactions were found for all outcomes (all p < 0.01), indicating CBT's specific efficacy. Discussion: This study provides the first RCT evidence that CBT significantly reduces both core MD symptoms and steroid-related psychopathology in men engaged in AAS/PED misuse. Improvements extended to mood, body image perception, and compulsive exercise behaviors. These findings support CBT's transdiagnostic applicability in addressing both the cognitive-behavioral and affective dimensions of MD. Materials and Methods: In this parallel-group, open-label RCT, 59 male gym-goers with DSM-5-TR diagnoses of MD and a history of AAS/PED use were randomized to either a 12-week CBT intervention (n = 30) or a waitlist control group (n = 29). CBT sessions were delivered weekly online and targeted distorted muscularity beliefs, compulsive behaviors, and emotional dysregulation. Primary and secondary outcomes-Muscle Dysmorphic Disorder Inventory (MDDI), PHQ-9, K10, EDE-Q, EAI, and BIG-were assessed at the baseline, post-treatment, and 3-month follow-up. A repeated-measures ANOVA and paired t-tests were used to analyze time x group interactions. Conclusions: CBT offers an effective, scalable intervention for individuals with muscle dysmorphia complicated by anabolic steroid use. It promotes broad psychological improvement and may serve as a first-line treatment option in high-risk male fitness populations. Future studies should examine long-term outcomes and investigate implementation in diverse clinical and cultural contexts.
Comparison of Domino Transplantation with Two-Way Paired Exchange and Normal Transplantation: Acute Rejection, Surgical Complications, and 5-Year Survival Outcomes
(Springer, 2025) Huseynov, Amil; Cicek, Sevim Nuran Kuslu
Background Domino kidney paired donation and Two-Way Paired Exchange have emerged as vital strategies to expand the donor pool in renal transplantation, especially for patients facing ABO or HLA incompatibilities. Despite their potential benefits, concerns remain regarding immunological risks, infectious complications, and long-term graft survival. Methods In this retrospective cohort study conducted at Medicana Transplant Center, 980 adult kidney transplant recipients were categorized into three groups: Domino (n = 144), Two-Way Paired Exchange (n = 350), and Normal Transplant (n = 486). Baseline characteristics, acute rejection rates, and surgical or infectious complications were collected, alongside data on 1-year and 5-year patient and graft survival. Statistical analysis included Kaplan-Meier survival curves and Cox proportional hazards modeling for independent predictors of graft outcomes. Results The Domino group had the highest 1-year acute rejection rate (17.4%) compared to Two-Way Paired Exchange (4.3%) and Normal Transplant (3.7%), yet 1-year graft survival rates remained comparable (92%, 95%, and 96%, respectively; p = 0.271). Infectious complications were more frequent in the Domino group (25%) than in others (p < 0.01). Extended follow-up to 5 years indicated no statistically significant difference in overall graft or patient survival among the three groups (log-rank p = 0.197), despite a trend toward lower 5-year graft survival in the Domino group. Donor-specific antibodies and higher HLA mismatches independently predicted acute rejection. Conclusions Domino transplantation, while associated with higher immunologic challenges, achieves acceptable short-term and 5-year outcomes akin to Two-Way Paired Exchange and Normal Transplant. Careful immunosuppressive strategies, vigilant monitoring, and collaborative protocols are integral for optimizing long-term success in high-risk transplant scenarios.
The Development and Validation of an Integrated Assessment of Irrational Beliefs Concerning Basic Psychological Needs: The Rational Emotive Self-Determination Scale for Workers
(Frontiers Media Sa, 2025) Artiran, Murat; Tinaz, Pinar; Simsek, Omer Faruk; Miller, Anthony; Vione, Katia Correa; Turner, Martin James
Introduction Recently a new approach to understanding human behaviour has emerged that integrates rational emotive behaviour therapy (REBT) from the cognitive behavioural tradition, and self-determination theory (SDT) from the humanistic tradition. In the current study, we develop a psychometric that conceptualizes this new approach in organisational settings; the rational emotive self-determination scale for work (RESD-W). The RESD-W assesses respondents' irrational beliefs (from REBT) concerning the basic psychological needs (from SDT), namely perceptions of autonomy, competence, and relatedness within their work life. The RESD-W builds on initial validations of the RESD in adolescent populations (RESD-A).Methods In the current paper, the psychometric properties of the 16-item RESD-W were examined across five studies, in which the factor structure, the reliability of the scale, and construct and criterion-oriented validity of the RESD-W were assessed.Results Analyses confirmed theoretical expectations and yielded good psychometric properties. Scores in the RESD-W were associated with anxiety and depression, and negative emotions in the workplace.Discussion The results are discussed regarding practice, highlighting that work related psychological wellbeing may be predicated on the integration of irrational beliefs and basic psychological needs.
Digital Detox: Exploring the Impact of Cybersecurity Fatigue on Employee Productivity and Mental Health
(Springer Nature, 2025) Mizrak, Filiz; Demirel, Hatice Gokce; Yasar, Okan; Karakaya, Turhan
This study investigates the growing phenomenon of cybersecurity fatigue and its implications for employee productivity and mental health in the high-demand sectors of information technology (IT), finance, healthcare and education. Utilizing a quantitative research methodology, the study surveyed 351 employees from these industries to analyze the relationships between cybersecurity fatigue, work efficiency, and mental health indicators, including stress and anxiety. The findings highlight cybersecurity fatigue as a significant factor contributing to burnout, reduced productivity, and increased psychological strain. Structural Equation Modeling (SEM) demonstrates the moderating effects of digital detox initiatives and mental health support strategies in mitigating fatigue and improving employee well-being and organizational performance. This research addresses a critical gap by focusing on the human dimensions of cybersecurity management and offers practical recommendations for simplifying protocols and fostering resilience. The study provides actionable insights for organizations operating under stringent cybersecurity requirements, enabling them to enhance employee satisfaction and performance.
Dynamic Quantitative Imaging of the Masseter Muscles in Bruxism Patients with Myofascial Pain: Could It Be an Objective Biomarker
(MDPI, 2023) Aydin Aksu, Sibel; Kursoglu, Pinar; Turker, Izim; Baskak, Fulya; Ozen Sutuven, Elifnaz; Meric, Kaan; Cabbar, Fatih
We aimed to investigate whether the collaboration of shear wave elastosonography (SWE) and B-mode ultrasonography (US) could be offered as diagnostic tools to assess the presence, severity, and progress of bruxism, as well as a biomarker for the effectiveness of treatment in daily clinical practice. The study was designed as a quantitative evaluation of the masseter muscles (MMs) of the clinically diagnosed bruxism patients suffering from myofascial pain and MMs of the healthy individuals. Clinical examinations were made according to the diagnostic criteria for temporomandibular disorders (DC/TMD), and pain was assessed using a visual analog scale (VAS). Painful MMs with VAS scores >= 4 were assigned to Group A, and healthy MMs were assigned to Group B. Also, the MMs of the painful bruxers were analyzed based on wearing occlusal splints. Group A was divided into two subgroups as splint users (Group AI) and non-users (Group AII). All the participants were scanned with dynamic US and SWE to quantify the size and stiffness of the MMs. Measurements of each muscle pair while the jaw is in a resting position (relaxation) and clenching position (contraction) were recorded. The significant differences in stiffness and thickness became visible in the relaxation state. Bruxism patients with myofascial pain had significantly harder and thinner MMs than healthy individuals. During the relaxation, the mean thickness and elasticity values were 9.17 +/- 0.40 mm and 39.13 +/- 4.52 kPa for Group A and 10.38 +/- 0.27 and 27.73 +/- 1.92 for Group B, respectively. Also, stiffer MMs were measured in Group AII (38.16 +/- 3.61 kPa) than in Group AI (26.91 +/- 2.13 kPa). In conclusion, the combination of SWE and US using a dynamic examination technique has the potential to be a valuable tool for the management of bruxism patients suffering from myofascial pain.
Effect of Multi-Artery Renal Grafts on Patient Outcomes in Living Donor Kidney Transplantation
(Springer, 2025) Huseynov, Amil; Sengul, Halil
BackgroundMultiple renal arteries (MRA) in a donor kidney can increase surgical complexity in living donor kidney transplantation. However, the impact of MRA on early transplant outcomes, including delayed graft function (DGF) and early graft failure, remains unclear.MethodsWe performed a single-center retrospective cohort study of 1,200 living donor kidney transplants conducted between 2019 and 2024. Donor kidneys were classified as having a single renal artery or multiple renal arteries (two or more). Recipient and donor characteristics, intraoperative details (ischemia times, vascular anastomosis technique), and postoperative outcomes (delayed graft function [DGF], primary nonfunction, and graft survival) were compared between the two groups. Logistic regression analyses were used to examine associations between MRA and the risk of DGF or graft failure within the first 90 days, both before and after adjusting for prespecified covariates.ResultsOf the 1,200 transplanted kidneys, 882 (73.5%) had a single artery and 318 (26.5%) had multiple arteries. Although the median cold-ischemia time was longer for multi-artery grafts (35.2 min vs. 29.4 min, p = 0.004), there were no significant differences in donor or recipient baseline characteristics. Multivariable logistic regression revealed no significant association between MRA and either DGF or early graft loss. Kaplan-Meier curves, censored for death, demonstrated similar graft survival in both groups (log-rank p = 0.25).ConclusionsIn this single-center cohort of living donor kidney transplants, grafts with multiple renal arteries did not exhibit an elevated risk of DGF or early graft loss. While additional surgical complexity is often required for MRA grafts, our findings suggest that these kidneys remain a safe and effective option for transplantation, supporting their broader use to expand the donor pool.
Effects of Mindfulness on Test Anxiety: A Meta-Analysis
(Frontiers Media Sa, 2024) Yilmazer, Eda; Hamamci, Zeynep; Turk, Fulya
Objective: This meta-analysis evaluated the effectiveness of mindfulness-based interventions (MBIs) on test anxiety across diverse age groups and intervention modalities. Methods: Rigorous inclusion criteria were applied to select studies focusing on MBIs as the independent variable, with test anxiety as the outcome. A comprehensive search across multiple databases yielded 18 primary studies, contributing 20 comparisons. Data were extracted on study characteristics, sample sizes, and intervention details, and were analyzed using a random-effects model. Results: The analyses incorporated 1,275 participants, with MBIs demonstrating a moderate to large negative effect on test anxiety (effect size = -0.716; 95% CI: -1.383 to -0.049). Moderation analysis indicated that mean age, number of sessions, and intervention delivery mode did not significantly influence effect sizes. Publication bias assessment suggested the presence of bias via Egger's regression (p = 0.025), though Begg and Mazumdar's test and Duval and Tweedie's trim and fill method indicated no missing studies. Conclusion: MBIs are effective in reducing test anxiety, though results should be interpreted with caution due to potential publication bias and unexplained heterogeneity. The impact of MBIs did not vary significantly with participant age, number of sessions, or delivery mode.
Efficacy of Cognitive-Behavioral Therapy in Reducing Muscle Dysmorphia Symptoms Among Turkish Gym Goers: A Pilot Study
(Elsevier, 2024) Cinaroglu, Metin; Yilmazer, Eda; Ulker, Selami Varol; Ahlatcioglu, Esra Noyan; Sayar, Gokben Hizli
Muscle dysmorphia (MD) is a disorder marked by an obsessive focus on muscularity, often leading to excessive exercise, rigid dieting, and use of performance-enhancing drugs (PEDs). While Cognitive-Behavioral Therapy (CBT) is known to be effective for various body image disorders, its specific effects on individuals with MD have been less studied. This qualitative case series involved seven male participants, aged 35-55, all diagnosed with MD and with a history of anabolic steroid use, undergoing a 12-week manualized CBT intervention. The study aimed to explore how CBT impacts their body image perceptions, exercise behaviors, steroid use, and emotional responses. Data were collected through participant feedback during therapy sessions, with thematic analysis revealing significant shifts in body image perception and reductions in compulsive behaviors and steroid use. Despite these improvements, participants experienced feelings of loss and anxiety as they modified their routines, and some reported relapses under stress, indicating the chronic nature of MD. The findings suggest that CBT effectively reshapes cognitive and behavioral patterns in MD sufferers but also highlight the need for ongoing support to manage the disorder's emotional complexities and prevent relapses. Future research should focus on long-term and individualized therapeutic approaches to better support those with muscle dysmorphia.
Factors Affecting the Presence of Renal Cortical Cysts in Kidney Donors
(Aves, 2024) Cicek, Sevim Nuran Kuslu; Huseynov, Amil
Objective: Simple renal cysts (SRCs) represent the most frequently occurring type of renal cysts, frequently observed in the elderly population. While generally considered benign, SRCs may sometimes be connected to comorbid conditions such as hypertension, aortic diseases, and renal dysfunction. This research aims to investigate the factors influencing the development of SRCs in kidney donors and the associated risks. Methods: This retrospective cohort study included 1012 living kidney donors, aged 18-87 years, who underwent renal transplant donor nephrectomy between 2008 and 2023. Data on demographic information, cyst characteristics, comorbidities, and associated risk factors were collected and analyzed using statistical methods, including Binary Logistic Regression Analysis. Renal cysts were identified and classified using computed tomography (CT) and magnetic resonance imaging (MRI) methods. Results: Renal cortical cysts were more frequently observed in males (52.76%) compared to females (47.24%), with a significant difference (P = .031). Donors with renal cortical cysts were significantly older (mean age 54.43 +/- 12.17 years) compared to those without cysts (46.26 +/- 12.35 years, P < .001). Substantial differences were likewise noted in fasting blood glucose, uric acid, creatinine, HbA1c, and glomerular filtration rate (GFR).The prevalence of aortic atherosclerosis was notably elevated in donors with cysts (47.74%) compared to those without (23.57%, P < .001). Binary logistic regression analysis indicated that older age and being male were significant factors influencing the presence of cortical cysts. Conclusion: The study confirms that SRCs are the most common renal cyst type and are more frequently observed in the elderly population. While generally benign, SRCs may be associated with increased uric acid levels and other comorbidities, suggesting potential impacts on kidney health. Additional studies are required to investigate these associations. The presence of SRCs in kidney donors is significantly associated with male gender, age, uric acid levels, and creatinine levels. These findings should be considered during the evaluation of potential kidney donors, particularly regarding the associated risks and management of SRCs.
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants with Treatment Resistance in Schizophrenia
(American Medical Association, 2022) Pardiñas, A.F.; Smart, S.E.; Willcocks, I.R.; Holmans, P.A.; Dennison, C.A.; Lynham, A.J.; Legge, S.E.
Importance: About 20% to 30% of people with schizophrenia have psychotic symptoms that do not respond adequately to first-line antipsychotic treatment. This clinical presentation, chronic and highly disabling, is known as treatment-resistant schizophrenia (TRS). The causes of treatment resistance and their relationships with causes underlying schizophrenia are largely unknown. Adequately powered genetic studies of TRS are scarce because of the difficulty in collecting data from well-characterized TRS cohorts. Objective: To examine the genetic architecture of TRS through the reassessment of genetic data from schizophrenia studies and its validation in carefully ascertained clinical samples. Design, Setting, and Participants: Two case-control genome-wide association studies (GWASs) of schizophrenia were performed in which the case samples were defined as individuals with TRS (n = 10501) and individuals with non-TRS (n = 20325). The differences in effect sizes for allelic associations were then determined between both studies, the reasoning being such differences reflect treatment resistance instead of schizophrenia. Genotype data were retrieved from the CLOZUK and Psychiatric Genomics Consortium (PGC) schizophrenia studies. The output was validated using polygenic risk score (PRS) profiling of 2 independent schizophrenia cohorts with TRS and non-TRS: a prevalence sample with 817 individuals (Cardiff Cognition in Schizophrenia [CardiffCOGS]) and an incidence sample with 563 individuals (Genetics Workstream of the Schizophrenia Treatment Resistance and Therapeutic Advances [STRATA-G]). Main Outcomes and Measures: GWAS of treatment resistance in schizophrenia. The results of the GWAS were compared with complex polygenic traits through a genetic correlation approach and were used for PRS analysis on the independent validation cohorts using the same TRS definition. Results: The study included a total of 85490 participants (48635 [56.9%] male) in its GWAS stage and 1380 participants (859 [62.2%] male) in its PRS validation stage. Treatment resistance in schizophrenia emerged as a polygenic trait with detectable heritability (1% to 4%), and several traits related to intelligence and cognition were found to be genetically correlated with it (genetic correlation, 0.41-0.69). PRS analysis in the CardiffCOGS prevalence sample showed a positive association between TRS and a history of taking clozapine (r2 = 2.03%; P =.001), which was replicated in the STRATA-G incidence sample (r2 = 1.09%; P =.04). Conclusions and Relevance: In this GWAS, common genetic variants were differentially associated with TRS, and these associations may have been obscured through the amalgamation of large GWAS samples in previous studies of broadly defined schizophrenia. Findings of this study suggest the validity of meta-analytic approaches for studies on patient outcomes, including treatment resistance. © 2022 Pardiñas AF et al.
Interhemispheric EEG Coherence as a Candidate Biomarker in Gambling Disorder: Evidence of Frontal Hyperconnectivity and Posterior Disconnectivity
(Frontiers Media SA, 2025) Yilmazer, Eda; Cinaroglu, Metin; Ulker, Selami Varol; Tarlaci, Sultan
Background Gambling Disorder (GD) is a behavioral addiction marked by impaired decision-making and poor impulse control. We investigated whether resting-state interhemispheric quantitative EEG (qEEG) coherence-a measure of functional connectivity between homologous cortical regions-could serve as a biomarker of GD.Methods Twenty-nine male patients with GD and 45 healthy male controls underwent resting-state qEEG recording. Coherence was computed for homologous electrode pairs across delta, theta, alpha, and beta bands. Group differences were analyzed using independent-samples t-tests; associations with disorder duration were assessed via age-controlled partial correlations.Results Consistent with our hypothesis, GD participants exhibited frontal pole hypercoherence (Fp1-Fp2) across delta, theta, and beta bands, which is likely influenced by prefrontal/orbitofrontal generators. In contrast, GD showed hypocoherence in temporal (T3-T4, T5-T6), central (C3-C4), and parietal (P3-P4) regions across these frequencies. Greater disorder duration was associated with lower beta coherence at F3-F4 and Fp1-Fp2, and higher delta coherence at O1-O2.Conclusions These findings reveal a dual pattern of interhemispheric connectivity disruption in GD-hypercoherence at frontal pole sites and hypocoherence in sensorimotor and attentional posterior networks-supporting theoretical models of addiction neurocircuitry. Resting-state qEEG coherence holds promise as a clinically relevant biomarker for GD and may inform the development of neuromodulatory interventions aimed at network rebalancing.
Investment Strategies for Renewable Energy Technologies and Harvesting Systems in Airport Operations Using Spherical Fuzzy MCDM Models
(Nature Portfolio, 2025) Mizrak, Filiz; Sahin, Didem Rodoplu
This study presents a novel evaluation framework for prioritizing investment strategies in sustainable airport energy systems by integrating advanced fuzzy decision-making techniques with artificial intelligence-based expert weighting. Specifically, it employs a hybrid Spherical Fuzzy CRITIC-RATGOS model to rank renewable energy alternatives based on economic feasibility, environmental impact, technological efficiency, scalability, and operational reliability. To address limitations associated with equal expert weighting, a Principal Component Analysis-driven dimension reduction technique is applied to calibrate expert influence based on professional background and consistency of evaluation. The model is applied to a real-world case study at Istanbul Airport, demonstrating that AI-optimized energy management, solar microgrids, and waste-to-energy conversion are the most promising investment alternatives. In contrast, although technologies such as piezoelectric harvesting show future potential, their current limitations reduce their immediate feasibility. Sensitivity analysis affirms the robustness and stability of the results across various weighting configurations. The proposed framework contributes to both theory and practice by offering a scalable, transparent, and replicable decision-support tool for airport authorities, policymakers, and energy planners aiming to align infrastructure development with global sustainability and decarbonization goals.
Job Demands, Resources, and Future Considerations: Academics' Experiences of Working from Home During the Coronavirus Disease 2019 (COVID-19) Pandemic
(Frontiers Media Sa, 2022) Karatuna, Isil; Joensson, Sandra; Muhonen, Tuija
The coronavirus disease 2019 pandemic has severely affected workers, workplaces, and working practices. In the higher education setting, universities have shifted to distance learning, resulting in profound changes in academics' work. In this study, we aimed to describe academics' job demands and resources related to changes in working conditions during the pandemic, and to examine how these changes have affected the perceived occupational wellbeing of academics. Additionally, we aimed to investigate academics' expectations and concerns for future academic working practices following the pandemic. The data were collected through semi-structured interviews with 26 academics working at various universities in Sweden. A content analysis was used to identify the key themes from the transcribed interviews. The results indicated that academics experienced a lack of face-to-face communication, absence of an academic environment, work overload, and work-home interference as demanding during the pandemic. In relation to resources, online communication options, appropriate working conditions, organizational-social support, and individual factors were perceived as important. Most respondents perceived negative occupational wellbeing outcomes. However, academics who had the appropriate resources were less likely to be affected by job demands. Academics' expectations for future academic work included continuation of working online, flexibility in the choice of workspace, and strengthened digital capacity. Their concerns were related to a lack of face-to-face interaction, management actions and economic implications, and pure digital education. This paper contributes to the literature by illustrating the complexity and diversity of experiences and preferences among academics that are important for universities to consider when organizing and managing future academic work.
Laparoscopic Hand-Assisted Donor Nephrectomy: A Decade of Single-Center Experience and Outcomes
(AVES, 2024) Cicek, Sevim Nuran Kuslu; Huseynov, Amil
Objective: Kidney transplantation is the most effective treatment for end-stage renal disease, but the shortage of cadaveric donors has increased reliance on living donors. Traditional open donor nephrectomy, while effective, is associated with significant morbidity. Hand-assisted laparoscopic donor nephrectomy (HALDN) combines the advantages of minimally invasive surgery with the tactile feedback of open surgery. This study presents the outcomes of HALDN procedures performed at the center. Methods: A total of 1221 living donor nephrectomies performed between September 2009 and August 2021 at Medicana & Idot;stanbul Hospital were analyzed. Donor characteristics, surgical details, and postoperative outcomes were recorded. Data analysis was conducted using SPSS version 22.0, with continuous variables assessed for normality and expressed accordingly. Results: Donor ages ranged from 19 to 87 years (mean 48.50 +/- 12.75 years), with 54.8% female donors. The average body mass index (BMI) was 27.99 +/- 3.7 kg/m2. Left-sided nephrectomies constituted 78.5% of cases, with HALDN performed in 94.7% of these surgeries. Warm ischemia time averaged 99.21 +/- 56.67 seconds. The average blood loss was 70 mL, and the mean hospital stay was 4.12 +/- 1.2 days. Complications included conversion to open surgery due to bleeding in 3.3% of cases, postoperative atelectasis (0.6%), incisional hernia (0.33%), wound infection (0.16%), and scrotal swelling (0.25%). The findings indicate that HALDN is a safe and effective method for donor nephrectomy, aligning with similar studies regarding operation and warm ischemia times. The minimally invasive nature of HALDN contributes to shorter hospital stays and quicker postoperative recovery. The rate of conversion to open surgery was within acceptable limits, and complications were manageable. Obesity (BMI > 30 kg/m2) was identified as a risk factor for incisional hernia, suggesting the need for careful surgical technique in this group. Conclusion: Hand-assisted laparoscopic donor nephrectomy offers a minimally invasive, safe, and effective alternative for living donor nephrectomy, enhancing donor recovery and potentially encouraging organ donation. Its adoption may play a significant role in reducing the number of patients awaiting organ transplants.
Measuring Remote Working Skills: Scale Development and Validation Study
(Public Library of Science, 2024) Benligiray, Serap; Gungor, Abdullah Y.; Akbas, Ilkay
Remote work, one of the most significant working arrangements of today, requires certain employee skills. Although there are some hints, there is not much information in the literature on this subject. This study aims to identify the skills required for productive remote working activities and to develop a scale for measuring these skills. For this purpose, a thorough review of the literature, consultation with experts, and analysis of data obtained from four samples with remote working experience were all conducted. Within this context, item generation and content validation, initial factor structure analysis, and factor structure confirmation and construct validity examination were performed. Consequently, the Remote Working Skills Scale was developed, which has 36 items and five dimensions (cybersecurity, problem-solving, time management, verbal communication, and written communication).
The Mediating Role of Cognitive Emotion Regulation Skills in the Relationship Between Romantic Relationship Satisfaction and Eating Attitudes
(Springer Nature, 2025) Yilmazer, Eda; Turk, Fulya; Hamamci, Zeynep
Background Romantic relationship satisfaction has been linked to psychological outcomes, including emotional well-being and eating behaviors. However, the mechanisms underlying this relationship remain unclear. This study examines the mediating role of cognitive emotion regulation strategies-particularly catastrophizing-in the relationship between romantic relationship satisfaction and eating attitudes. Methods A cross-sectional study was conducted with 355 university students. Participants completed the Relationship Satisfaction Scale, the Cognitive Emotion Regulation Questionnaire (CERQ), and the Eating Attitudes Test-26 (EAT-26). Structural equation modeling (SEM) was performed using AMOS and R with robust maximum likelihood estimation. Model fit was evaluated using chi 2/df, CFI, GFI, RMSEA, and SRMR. Results Catastrophizing significantly mediated the relationship between romantic relationship satisfaction and eating attitudes. Romantic relationship satisfaction was negatively associated with catastrophizing (beta = -0.18, p = .028), and catastrophizing was positively associated with problematic eating attitudes (beta = 0.35, p < .001). The direct effect of romantic relationship satisfaction on eating attitudes was not statistically significant (beta = -0.12, p = .104), indicating full mediation. Acceptance did not significantly mediate the relationship (p = .348). Gender differences were observed: women scored significantly higher on rumination, dieting, and bulimia/food preoccupation (p < .05). Conclusions These findings highlight the role of maladaptive cognitive emotion regulation-specifically catastrophizing-in linking romantic relationship dissatisfaction with disordered eating attitudes. Targeting catastrophizing in interventions may improve both relationship satisfaction and eating behaviors.
Mediating Role of Psychological Maladjustment in Relation Between Dark Triad, Psychological Distress and Subjective Happiness of Pakistani Emerging Adults
(Frontiers Media Sa, 2022) Mushtaq, Asia; Inam, Ayesha; Najmussaqib, Arooj; Afshan, Anjum; Ermagan-Caglar, Eda
The transition from adolescence to adulthood is fraught with challenges that might have impacts on later life and personality development. Earlier research investigated Dark Triad traits in connection to emotional problems. The current study, on the other hand, focused on investigating the mediating role of psychological maladjustment in the relation of Dark Triad traits, psychological distress, and subjective happiness in emerging adults. A sample of 546 participants aged 18-25 years (M = 21.2 years) from Pakistan have participated to complete an online survey. Standardized assessment tools were used to measure the targeted variables. Results indicated that Machiavellianism and psychopathy were positively associated with psychological distress, whereas narcissism appeared to be a non-significant predictor. Subjective happiness was positively associated with Machiavellianism and negatively associated with psychopathy. In addition, mediation analysis through Structural Equation Modeling (SEM) indicated that the Dark Triad traits (Machiavellianism and psychopathology), psychological distress, and subjective wellbeing were explained by psychological maladjustment. Implications and limitations are discussed.
Multimodal Neurophysiological Responses to Body Image Stimuli in Men with Muscle Dysmorphia and Steroid Use
(Elsevier, 2025) Cinaroglu, Metin; Yilmazer, Eda; Ulker, Selami Varol; Sayar, Gokben Hizli
Muscle dysmorphia (MD), a subtype of body dysmorphic disorder (BDD), involves a pathological preoccupation with muscularity and is commonly linked to anabolic steroid and performance-enhancing drugs (PEDs) use. Despite its rising prevalence, the neurophysiological and affective mechanisms underlying MD, particularly in steroid users, remain underexplored. This study examined 71 male strength-training participants (35 with BDD/ steroid use; 36 controls) during a passive viewing task of muscular, average, and slender male physiques while recording electroencephalography (EEG), electrodermal activity (EDA), and eye-tracking data. Psychometric assessments captured muscularity concerns (Muscle Dysmorphic Disorder Inventory, MDDI), anxiety (State-Trait Anxiety Inventory, STAI), obsessive-compulsive symptoms (Obsessive-Compulsive Inventory-Revised, OCI-R), appearance-related anxiety (Social Appearance Anxiety Scale, SAAS; Social Physique Anxiety Scale, SPAS), and selfesteem (Self-Liking/Self-Competence Scale-Revised, SLCS-R). The BDD/MD group showed significantly heightened responses to muscular stimuli across all modalities. EEG results revealed increased P300 and late positive potential (LPP) amplitudes, along with greater left-lateralized frontal alpha asymmetry. Eye-tracking indicated longer fixation durations and more frequent fixations on muscular images. EDA results showed elevated levels of autonomic arousal. Between-group differences in psychometric measures were substantial, with large effect sizes. Correlational analyses demonstrated significant associations between MD severity and neurophysiological markers, including LPP amplitude, frontal asymmetry, and EDA reactivity. These findings suggest that men with MD and steroid/PEDs use exhibit amplified attentional, emotional, and physiological reactivity to muscular body images. The integration of EEG, EDA, and eye-tracking provides novel insights into the neurocognitive-affective profile of BDD/MD, emphasizing the salience of idealized physiques in this population. Results support the potential utility of multimodal measures as objective indicators for assessing body image disturbance and underscore the need for targeted interventions addressing perceptual and emotional dysregulation in BDD/MD.

Browse

Browsing PubMed İndeksli Yayınlar Koleksiyonu by Access Right "info:eu-repo/semantics/openAccess"