Mühendislik ve Mimarlık Fakültesi

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Alterations in Niban Gene Expression as a Response to Stress Conditions in 3t3-L1 Adipocytes
(Springer, 2020) Cevik, Mehtap; Gunduz, Meliha Koldemir; Deliorman, Gokce; Susleyici, Belgin
Adipocyte death is important in obesity development. Understanding and prevention of adipocyte deaths may be a molecular approach in the treatment. In the study, we aimed to understand role of Niban gene, which acts as an anti-apoptotic molecule as a response to stress conditions, in adipocytes. 3T3-L1 adipocytes were treated with different doses of linoleic acid, hydrogen peroxide and ethanol; and proliferation of the cells examined with real time monitoring iCELLingence system. Gene expression levels were measured by q-PCR. As a response to 24h 480 mu M linoleic acid treatment, Niban gene expression was found to be higher than control group (p = 0.008), whereas 24 h 90 mM ethanol treatment was determined to be lower than control group (p = 0.008). The highest value of Niban gene expression among H2O2 treatment groups was detected in 4h 600 mu M H2O2 in comparison to control group (p = 0.008). To understand role of Niban in adipogenesis, Niban gene expressions were compared between pre-adipocytes and advanced fat accumulated adipocytes and determined to be significantly different (p = 0.042). Our results suggest that Niban might be involved in stress response process in adipocytes. However, the exact molecular role of Niban needs to be investigated in further studies.
Cd Dopant Effect on Structural and Optoelectronic Properties of TiO2 Solar Detectors
(Springer, 2021) Ilhan, Mustafa; Koc, Mumin Mehmet; Coskun, Burhan; Erkovan, Mustafa; Yakuphanoglu, Fahrettin
Al/n-Si/Ti1-xO2CdxO/Al photodiodes were produced using sol-gel and spin coating methods where CdO dopant was applied on different concentrations (x = 0.0; x = 0.01; x = 0.05; x = 0.10). Cd dopant effect upon structural, optical, photodiode and electrical properties was assessed. Scanning electron microscope and energy-dispersive spectra were used in the structural investigation. Optic properties were assessed using UV-Vis spectroscopy and bandgap energies of the photodiodes were calculated which were found to be between 3.25 and 3.36 eV. Increased bandgap energy was observed with increased CdO doping rate. Photodiode properties were assessed under varying daylight illuminations. Barrier height, ideality factor, dark current, linear dynamic rate, photosensitivity, photoresponsivity of the photodiodes were calculated. Electrical properties of the Al/n-Si/Ti1-xO2CdxO/Al photodiodes were calculated where conductance-voltage and capacitance-voltage plots were obtained. Corrective conductance-voltage and corrective capacitance-voltage graphs confirm that the electrical properties of the photodiodes depend on AC signal frequency. Frequency-dependent electrical characteristics were attributed to the density of interface states which were found to be between 10(11) and 10(12). Decreased density of interface state was found for increased AC signal frequency.
Effect of Heat Treatment on Magnetic Properties of Nanocomposite Nd-Lean Nd7Fe73b20 Ribbons
(Springer, 2021) Caglar, Seyit; Kilicaslan, M. Fatih; Atasoy, Ahmet; Tiryaki, Hasan; Erkovan, Mustafa; Hong, Soon-jik
In this work, we explored the effect of heat treatment on high boron and Nd-lean content magnetic Nd7Fe73B20 nanocomposite materials via vibration sample magnetometer (VSM), X-ray diffraction, differential thermal analysis (DTA), and scanning electron microscope (SEM). The Scherer formula was employed to estimate the effect in the crystal size of the heat treatment on high boron and Nd-lean content magnetic Nd7Fe73B20 nanocomposite materials. We heat-treated samples in different conditions to obtain optimum magnetic properties. Our high-throughput fabrication strategy allows us to elucidate the possibility of obtaining Nd-lean nanocomposite NdFeB magnet in terms of the melt-spinning. We evaluated the influence of heat treatment on the Nd-lean NdFeB/alpha-Fe nanocomposite magnets produced by melt-spinning. Here, in the heat-treated ribbon at 750 degrees C for 30 min, we obtained a combination of coercivity of 450 Oe, a high-saturation magnetization of 232 emu/g in the heat-treated ribbon at 650 degrees C for 30 min, which surpasses most traditional nanocrystalline magnets based on Fe-Co and pricey. The results we present here are expected to serve as a guideline for designing new magnets for industrial applications.

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