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Browsing Fakülteler by Department "Beykoz Üniversitesi Mühendislik ve Mimarlık Fakültesi"
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Article Alterations in Niban Gene Expression as a Response to Stress Conditions in 3t3-L1 Adipocytes(Springer, 2020) Cevik, Mehtap; Gunduz, Meliha Koldemir; Deliorman, Gokce; Susleyici, BelginAdipocyte death is important in obesity development. Understanding and prevention of adipocyte deaths may be a molecular approach in the treatment. In the study, we aimed to understand role of Niban gene, which acts as an anti-apoptotic molecule as a response to stress conditions, in adipocytes. 3T3-L1 adipocytes were treated with different doses of linoleic acid, hydrogen peroxide and ethanol; and proliferation of the cells examined with real time monitoring iCELLingence system. Gene expression levels were measured by q-PCR. As a response to 24h 480 mu M linoleic acid treatment, Niban gene expression was found to be higher than control group (p = 0.008), whereas 24 h 90 mM ethanol treatment was determined to be lower than control group (p = 0.008). The highest value of Niban gene expression among H2O2 treatment groups was detected in 4h 600 mu M H2O2 in comparison to control group (p = 0.008). To understand role of Niban in adipogenesis, Niban gene expressions were compared between pre-adipocytes and advanced fat accumulated adipocytes and determined to be significantly different (p = 0.042). Our results suggest that Niban might be involved in stress response process in adipocytes. However, the exact molecular role of Niban needs to be investigated in further studies.Editorial The Effects of Transportation Modes on Campus Use: A Case Study of a Suburban Campus(Elsevier Science Bv, 2019) Gocer, Ozgur; Gocer, KenanConference Object Efficient Shared Path Protection Routing for Survivable Optical WDM Networks(Institute of Electrical and Electronics Engineers Inc., 2019) Erkan, O.F.; Erkan, O.Sustainability of the service continuity provided in the optical wavelength division multiplexing (WDM) networks with dynamic traffic environment requires effective protection schemes in the connections. Various approaches have been introduced for path protection and wavelength assignment to ensure survivability in WDM networks. In this paper, we propose a two-step algorithm to designate dedicated-path and shared-path protection schemes. The heuristic-based algorithm utilizes a global labeling which considers service time and line protection information. Thus, the algorithm aims to increase resource utilization by improving the efficiency of shared path protection. The proposed algorithm is applied to USNET and EuropeNet networks and performance analysis in terms of blocking probability and resource utilization is carried out. © 2019 IEEE.Article Introduction of a Spatio-Temporal Mapping Based POE Method for Outdoor Spaces: Suburban University Campus as a Case Study(Pergamon-Elsevier Science Ltd, 2018) Gocer, Ozgur; Gocer, Kenan; Basol, Altug M.; Kirac, M. Furkan; Ozbil, Ayse; Bakovic, Mujesira; Ozcan, BarisOutdoor spaces are important to sustainable cities because they establish a common identity for social life by improving quality of urban living. The relation between outdoor spaces and building groups, competency, use period, and interaction of micro-climatic factors are needed to be investigated from a holistic approach. Unfortunately, the limited and narrow scoped POE studies on outdoor spaces make an overall assessment without causality relation. Other existing studies in outdoor spaces are mostly grouped under the headings such as; user satisfaction, space syntax and behavioral mapping, and biometeorological assessments. The intention of this paper is to introduce a new post-occupancy evaluation (POE) method integrates these studies focusing on various problems in outdoor spaces using spatio-temporal mapping. The comprehensive methodology applied in this research attempted to overcome some of the shortcomings of related studies by conducting a longitudinal study (during a year, as opposed to a few days) and also by objectively analyzing the associations of user behavior and physical attributes as well as the configurational properties of the campus layout. With this method, outdoor spaces can be evaluated in the context of the interaction between the physical environment and its users' behavior and activities, level of satisfaction and perceptions of comfort. The method has been applied on a suburban university campus in Istanbul, Turkey. The main courtyard of the campus has been subjected for map creation and result discussions.Book Part The Marketization of Higher Education in Turkey (2002-2011)(Palgrave, 2012) Onal, Nevzat EvrimArticle Marx’ın Üretken ve Üretken Olmayan Emek Ayrımının Beyaz Yakalı Emeğin Kategorileştirilmesinde Önemi(2019) Önal, Nevzat EvrimKapitalist üretim biçimi dahilinde, sermayenin yeninde üretim döngüsü içerisinde rol üstlenen emeğin analizi, bu analiz zorunlu olarak politik sonuçlara da sahip olacağı için daima sorunlu bir mesele olagelmiştir. Neoliberalizmle birlikte toplam sermaye birikimi içerisinde ticari ve finansal sermayenin; buna paralel olarak işçi sınıfı içerisinde de beyaz yakalı kesimin ağırlığının artması, bir kez daha tartışmayı alevlendirmiş; kafa ve kol emeği ayrımı sermaye birikim sürecinde zorunlu bir işbölümüne işaret etmekten ziyade işçi sınıfı içerisinde müstakil bölmeler tanımlamak, hatta beyaz yakalı bölmeyi işçi sınıfının dışına çıkartmak için kullanılır olmuştur. Öte yandan, ortada incelenmesi ve teorize edilmesi gereken bir fenomen olduğu açıktır. Bu çalışma, beyaz yakalı işlerde istihdam edilen emek gücünün halen sağlıklı biçimde kategorize edilememiş olduğu değerlendirmesinden yola çıkarak, klasik politik iktisat ekolü tarafından ortaya atılan ve en gelişkin haline Marx’ın bu ekole yönelik eleştirisinde ulaşan “üretken emek” ve “üretken olmayan emek” kavramsallaştırmasının bu sorunsal açısından kafa ve kol emeği ayrımından çok daha sağlıklı bir araç olduğunu savunmaktadır ve bu yönde bir uygulama denemesidir.Article Nano and Micro Satellites as the Pillar of the “New Space” Paradigm(2020) İnce, FuatSix decades after the launch of the first satellite in 1957, space business and space technologies are taking a new turn: From big to small, from primarily government to extensively private sector and from a few players to profusely many. The new paradigm, or “New Space”, as it has been called, can be characterized by new startups with venture capital backing entering the field or in fact leading the field in new innovative applications, universities and countries with no previous space experience joining the bandwagon, lean design and development techniques benefitting from the newly available COTS parts and subsystems, mass production of satellites, constellations of hundreds or thousands of small satellites serving old and new emerging niche needs, small launchers available for reaching orbit at low cost and rather short notice, capability to launch a rocket several times a month, and more exotic applications such as the coming space tourism and asteroid mining. Although there were initiatives in this direction in the previous century, they proved too feeble to set a trend. “New Space” started showing its first signs of emergence after the turn of the millennium. However the market acceptance has really taken root in the last 3 or 4 years. Market data clearly shows an accelerated pace shaping the future of space industry. This paper reviews the developments in the nano and micro satellites considering them as the pillar of the New Space paradigm. The road leading to the present state and the current trends are elaborated. A look to the future points to the proliferation of space applications among the many startups, big and small institutions, however being limited by market forces and survival by a few as the decade proceeds.Article Özelleştirmenin Tarımsal Destekler Ve Küçük Ölçekli Çiftçilik Üzerine Etkileri: Türkiye Deneyimi (1998-2012)(2016) Önal, Nevzat EvrimTürkiye'nin tarım sektörü cumhuriyetin ilk yıllarından itibaren kapitalist ekonominin gelişme doğrultusuna uygun, evrimsel bir dönüşüm geçirmiş ve bu dönüşüm çerçevesinde büyük toprak sahipleri ile küçük üreticilerin bir arada var olduğu bir yapı ortaya çıkmıştır. 20. yüzyılın son yıllarına dek bu yapının, onu bir arada tutan en önemli unsuru, devletin tarım sektörüne verdiği sübvansiyonlardı. Bu sübvansiyonlar, küçük üreticiler üzerinde piyasanın olumsuz etkilerini ve öngörülemezliğini bir ölçüde azaltmakta ve üretimi teşvik eder nitelikteydi. Ne var ki, 1990'ların ortasından itibaren finansal açıdan önce istikrarsız, ardından da sürdürülemez hale gelen kamu kesimi ekonomisinde, tarımsal destekler ortadan kaldırılması gereken bir harcama kalemi olarak öne çıktı. 1999'da IMF danışmanlığında başlatılan yapısal uyum programı, 2001 krizinin ardından Güçlü Ekonomiye Geçiş Programı olarak sürdürüldü ve bu süreçte devletin tarımsal destek sistemi büyük ölçüde tasfiye edildi. Bu tasfiyede, tarımsal desteklerin sağlanmasında kullanılan kurumların özelleştirilmesi önemli bir yöntem olarak öne çıktı. Bu çalışma, yaşanan tasfiyenin tarım sektöründeki sonuçları ve tarımsal istihdama etkilerini incelemektedir.

