WoS İndeksli Yayınlar Koleksiyonu

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Accreditation of Communication Education in Turkiye: Research on the Views of Administrator Academicians in Accredited Programs
(Istanbul Univ, Fac Communication, 2023) Kaygusuz, Erdinc
The subject of this study is an examination of how communication programs are accredited in Turkiye in the context of the views of administrator academicians. The research aims to explore the views of administrator academicians who are deans, vice deans, or heads of departments in their institutions regarding the accreditation of communication education in Turkiye. The study interviews 11 administrator academicians working in accredited undergraduate programs under communication faculties or the other faculties in which communication programs are included Turkiye, with the study sample being selected using multi-stage sampling. Proportional stratified and purposive sampling was also used to ensure that the groups in the universe are represented in proportion to their weights. Although minor problems exist in practice, accreditation has been concluded to play a developing role for institutions. Accordingly, accreditation allows institutions to renew, to correct the deficiencies in their organizational chart, to update the curriculum, to strengthen the teaching staff, to increase physical environments and opportunities, and to develop financial resources. In this respect, accreditation in communication education in Turkiye is seen as a concrete output rather than a corporate reputation provider. The findings support other studies that have focused on the benefits of accreditation.
Action Research About Development of Student's Artistic Form of Expression by Conceptual Art Activities
(Ani Publishing, 2019) Basar, Cigdem Tanyel; Ince, Metin
Since the 1960's, rapid changes and transformations in the field of art have been experienced in the light of the technological and social developments that have been experienced, and the expression forms and thought forms of today's art have differentiated. With this change in the art, there was a need for a new structuring and planning in the field of art education. The purpose of this research is to demonstrate how students' original expression patterns in artistic production have been improved through conceptual art practices. The research was designed with an action research model. Participants of the research consist of 12 undergraduate students who took Graphic Design lesson in Fine Arts Education Department of Anadolu University in the fall semester of 2012-2013 and the researcher conducting the course. Data were collected from class video records, semi-structured interviews, student diary, researcher diary, student objects/products and social media interactions. Data of the research were resolved through thematic analysis method. According to findings, it has been seen that the students have developed awareness of their surroundings by experiencing the research and inquiry process. The students have changed their conceptions of art and their distant attitudes to contemporary art and have tried to make meaning. From the research findings, students can be taught various artistic approaches such as art history, visual culture, digital art and contemporary art practices.
The Association of Subordinates' Perception of the Manager's Ambiguous Behaviors with the Likelihood of Conflict Occurrence: A Cross-Cultural Study
(IACM-NCMR-INT Assoc Conflict Management, 2024) Honuk, Hizir; Kucuk, Burcu Aydin; Caglar, Cihan Tinaztepe
The research aims to provide evidence to explain the contradictive findings in the literature on the organizational conflict phenomenon and the relationship between conflict and culture, by focusing on the relationship between ambiguous behaviors and conflict. To achieve this goal, in the context of low-status compensation theory, the relationship between incivility, humor as ambiguous behaviors, and the likelihood of manager- subordinate conflict occurrence was investigated. To test the culture's effect on this relationship, survey data were collected from 478 white-collar subordinates working in SMEs in Turkey and the UK. According to the results, the subordinate's perception of the manager's ambiguous behaviors affects the likelihood of relationship conflict and task conflict occurrence. In addition, the study reveals that culture is associated with the likelihood of relationship conflict occurrence but not task conflict. The study contributes to the literature by providing evidence for the relationship between humor, incivility, conflict, and culture.
Can Sustainability Reporting Make a Difference?: A Qualitative Analysis on Sustainability Reports of BIST Listed Agri-Food Companies in Turkey
(Ege Univ, Fac Economics & Admin Sciences, 2024) Gürsoy, Özgür Burçak; Akbas, Ilkay
Agri -business is a huge industry, including all operations from farm -level production to storage, manufacture, and distribution of agricultural commodities. This fact, together with worsening social and environmental conditions and pandemic crises, has added to a change in the perception of agriculture in economic construction. The following decades will most probably witness a resurgence of agriculture -based development recipes fed by social, environmental, and governance dimensions of sustainability. This article searches for the sustainability reports of agri-business firms listed in BIST in Turkey. A sampling includes 11 out of 64 listed agri-business firms having recent sustainability reports, which are examined by qualitative data analysis techniques with MAXQDA software. The first argument our findings support is that the agri-food sector is lagging in sustainability reporting compared to other sectors. Second, companies are more ready to comply with issues that are legally regulated. Third, environmental problems are more addressed than social and economic sustainability standards. This study also shows the relative unimportance of topics such as child labor, pesticide use, supply chain traceability, women entrepreneurship, and geographical indication, which can have positive impacts on the Turkish agricultural space if big companies integrate these topics more into their sustainability reporting processes. This article contributes to the literature on sustainability in general and reporting in the agri-food sector in particular.
Comparison of Different Heuristics Integrated with Neural Networks: A Case Study for Earthquake Damage Estimation
(Istanbul Univ, 2022) Malkocoglu, Ayse Berika Varol; Orman, Zeynep; Samli, Ruya
Earthquakes are among the most challenging natural phenomena to predict. Most of these unpredictable earthquakes result in the loss of human lives and property. Seismologists can estimate the probable location and magnitude of such earthquakes. However, the actual time and extent of their impact remain unknown. If the effects of possible earthquakes can be predicted, quick and accurate decisions can be made. For this purpose, developing predictive models about earthquakes is a prevalent and vital issue in the literature. In this study, various Machine Learning (ML) algorithms were compared on a public dataset of earthquakes, which had occurred worldwide and had a local magnitude Ml >= 3, and the algorithm with the highest performance was selected and optimized with various other algorithms. The performances of the models were compared using different performance evaluation metrics such as accuracy, Mean Square Error, Root-Mean Square Error, precision, recall, and f1 score. As a result, it was observed that the Artificial Neural Network (ANN) algorithm optimized with the Particle Swarm Optimization (PSO) algorithm produced the most successful result with an accuracy value of 0.82. Based on the obtained results, it is believed that this model can be used in different earthquake damage prediction studies and as a guide in emergency planning
Correspondence Concerning This Article Should Be Addressed Sent To Fulya Türk
(Int Inst Advanced Studies Psychotherapy & Applied Mental Health, 2025) Turk, Fulya; Kul, Aykut; Hamamci, Zeynep; Sungur, Mehmet Zihni; Sahin, Sengul Kocamer; Elboga, Gulcin
The global COVID-19 pandemic has exerted profound physical and psychological tolls on healthcare professionals, underscoring the urgent need for their mental health support. The objectives of this research are twofold: first, to develop an e-psychological support program based on Cognitive-Behavioral Therapy tailored specifically for healthcare professionals during the COVID-19 pandemic; second, to assess the program's effectiveness in reducing secondary traumatic stress, depression, anxiety, and stress levels, as well as improving healthcare professionals' perception of coping with trauma. Designed as a randomized controlled trial, the study was conducted with 71 healthcare workers employed in a hospital in Gaziantep, Turkey. The developed e-psychological support program consists of six modules: stress model, self-monitoring skills, coping with anxiety, behavioral activation skills, and cognitive restructuring (two modules). The results showing a significant decrease in anxiety, depression, stress and secondary traumatic levels in the intervention group compared to the control group are encouraging. This suggests that the CBT-based e-psychological support program has the potential to have a positive impact on the mental well-being of healthcare professionals. Also, the improvement in healthcare professionals' perception of coping with trauma is an important outcome.CBT has a strong evidence base for treating mental health issues, and adapting it for the specific needs of healthcare workers during a crisis like the pandemic is a promising approach. The development of online interventions for healthcare professionals is valuable not only for the current pandemic but also for future crisis situations. These programs can serve as a template for addressing mental health needs during other global health emergencies.
Design and Simulation of the Microcantilever Biosensor for MITF Antigen and D5 Monoclonal Antibody Interaction Finite Element Analysis, and Experimental
(Bentham Science Publishing Ltd, 2024) Akcali, Pelin; Kelleci, Kubra; Ozer, Sevil
Background Biosensors and MEMS have witnessed rapid development and enormous interest over the past decades. Constant advancement in diagnostic, medical, and chemical applications has been demonstrated in several platforms and tools. In this study, the analytical and FEA of the microcantilever used in biomolecular analyses were compared with the experimental analysis results.Methods In this study, MITF antigen, which is a melanoma biomarker, and anti-MITF antibody (D5) were selected as biomolecules. A MEMS-type microcantilever biosensor was designed by functionalizing the AFM cantilever by utilizing the specific interaction dynamics and intermolecular binding ability between both molecules. Surface functionalization of cantilever micro biosensors was performed by using FEA. The stress that will occur as a result of the interactions between the MITF-D5 has been determined from the deviation in the resonant frequency of the cantilever.Results It has been found that the simulation results are supported by analytical calculations and experimental results.Conclusion The fact that the results of the simulation study overlap with the experimental and mathematical results allows us to get much cheaper and faster answers compared to expensive and time-consuming experimental approaches.
Detection of Damaged Structures from Satellite Imagery Processed by Autoencoder with Boruta Feature Selection Method
(AVES, 2023) Muzoglu, Nedim; Adiguzel, Ertugrul; Akbacak, Enver; Karaslan, Melike Kaya
Many worldwide changing events, including meteorology, weather forecasting, disaster response, and environmental monitoring, are tracked by states or companies via satellite imagery. Early response to disasters is critical for human life. In these cases, artificial intelligence applications are also used to make rapid determinations about large geographical region. In this study, satellite images of flooded and undamaged structures in Hurricane Harvey were used. An autoencoder process has been applied to this dataset to reduce the noise in satellite imagery. AlexNet and VGG16 deep learning (DL) models are used to extract features from both datasets. The most effective features selected by the Boruta feature selection algorithm were classified with the support vector machine, and the highest classification accuracy of 99.35% was obtained. Since disasters involve the evaluation of very big datasets from large geographic areas, presenting the data with the smallest possible feature will facilitate the process. For this reason, by applying dimensionality reduction to the selected attributes, a 98.29% success was achieved in the classification with only 90 attributes. The proposed approach shows that DL and feature engineering are very effective methods to quickly respond to disaster areas using satellite imagery.
The Effects of SNAI1 rs6125849 Gene Polymorphism on Metastasis and Survival in Colorectal Cancer: Preliminary Results from Turkish Subjects
(Elsevier, 2021) Cevik, Mehtap; Namal, Esat; Sener, Nur Dinc; Koksal, Ulkuhan Iner; Deliorman, Gokce; Ciftci, Cavlan; Susleyici, Belgin
Background: Since metastasis is one of the leading causes of high mortality in colorectal cancer, uncovering the molecular mechanisms underlying metastatic process has become important to find new treatment approaches. With this perspective, in this study we investigated effects of epithelial-mesenchymal transition (EMT) inducer SNAI1 rs6125849 gene polymorphism on different features of colorectal cancer. Material and methods: A total of 141 Turkish subjects consisting of 72 colorectal cancer patients and 69 healthy controls were included in the study. SNAI1 rs6125849 genotype analyses were performed with Agena MassARRAY platform. Results: We did not find any significant difference between case and control groups for rs6125849 genotypes. All metastatic patients were detected to have homozygous mutant (AA) genotype. Heterozygous and homozygous mutant genotypes (GA + AA) were more common in metastatic colorectal cancer patients compared to those with homozygous wild type (GG) genotype (p = 0.066). We also detected positive, albeit low but significant correlation between rs6125849 genotypes in codominant and dominant models (r = 0.250, p = 0.034 and r = 0.234, p = 0.048, respectively). Overall survival times was found to be considerably higher patients with A allele (Log rank: 3.04, p = 0.081). Conclusion: According to our preliminary results, we may speculate that SNAI1 gene G > A variation may result with a metastatic phenotype and shorter overall survival. Due to limited number of patients in our study group, further in vitro and in vivo studies are required to understand the role of SNAI1 rs6125849 variation on metastasis and survival functions.
Evaluation of the Descriptive Values and Occlusion Effects of Air and Bone Conducted Cervical Vestibular Evoked Myogenic Potentials in Normal Individuals
(Springer, 2022) Tasci, Betul; Gencturk, Ertugrul; Serbetcioglu, Mustafa Bulent
Objective:This study was aimed to establish the descriptive statistical values of cVEMPs's responses which are evoked by air and bone conducted stimuli and to examine the effects of occlusion on bone conducted (BC) cVEMPs test. Methods:The study was carried out on 20 individuals (n = 40 ears), 11 women and 9 men, at the Medipol Mega University Hospital. cVEMPs tests were applied in five stages to the individuals who are volunteer to participate in this study. Firstly, the air conducted (AC) cVEMPs test was applied. Then, BC cVEMPs tests were applied in four different conditions with the aim of examining the occlusion effect. Results:Latency values of the AC cVEMPs response were 15.17 +/- 0.77 ms for P1 and 24.12 +/- 1.38 ms for N1 and 8.95 +/- 1.12 ms for interpeak latencies. P1N1 amplitude value was 149.73 +/- 75.00 mu V. VEMPs asymmetry ratio (VAR) was 0.16 +/- 0.16. Latency measurements of the BC cVEMPs response were 14.38 +/- 0.85 ms for P1 and 23.40 +/- 1.50 ms for N1 and 9.05 +/- 1.57 ms for interpeak latencies. P1N1 amplitude value was 107.58 +/- 54.08 mu V. VAR was 0.15 +/- 0.12. Both AC cVEMPs and BC cVEMPs parameters were demonstrated that there are not any significant differences between female-male and left ear-right ear. When AC and BC cVEMPs responses were compared, the mean P1 and N1 latencies of BC cVEMPs were significantly shorter than those of AC cVEMPs (p < 0.01). The mean amplitudes of AC cVEMPs were significantly larger than those of BC cVEMPs (p < 0.01). When the impact of the occlusion effect on cVEMPs parameters was examined, no statistical significance was found. Conclusion:As a result, it was thought that the BC cVEMPs, which is not widely used in clinics, might be used in the vestibular assessment of conductive hearing losses (CHL) in clinics, by obtaining descriptive values with this study. In addition, it was thought that it might be used as an auxiliary test to diagnose patients with hyperacusis who are disturbed by loud noises.
Exploring the Psychological and Social Dynamics of Steroid and Performance-Enhancing Drug (PED) Use Among Late Adolescents and Emerging Adults (16-22): A Thematic Analysis
(MDPI, 2025) Cinaroglu, Metin; Yilmazer, Eda; Noyan Ahlatcioglu, Esra
Background: Performance-enhancing drug (PED) use has become increasingly prevalent among adolescents and emerging adults, not solely for athletic advantage but as a psychological and sociocultural coping mechanism. In T & uuml;rkiye, where Westernized body ideals intersect with traditional values, the emotional and symbolic meanings of PED use among youth remain underexplored. Methods: This qualitative study employed semi-structured interviews and reflexive thematic analysis to examine the subjective experiences of 26 Turkish adolescents and emerging adults (19 males, 7 females; ages 16-22) in Istanbul who reported non-medical use of steroids or other PEDs. Participants were recruited through snowball sampling in gym-adjacent communities across six urban districts. Interviews were conducted online, recorded, transcribed, and analyzed to identify emergent psychological themes. Results: Six interconnected themes were identified: (1) body-based insecurity and the fantasy of reinvention; (2) emotional regulation through bodily control; (3) secrecy as autonomy; (4) compulsive enhancement and dissatisfaction; (5) psychological dependency and regret; and (6) PED use as agency and protest. While male and female participants differed in aesthetic goals and social narratives, both groups framed PED use as a means of identity construction, emotional survival, and social validation. Participants did not perceive themselves as deviant but as strategic actors navigating a performance-driven culture. Conclusions: PED use among youth in urban T & uuml;rkiye emerges as a psychologically embedded coping mechanism rooted in emotional regulation, self-concept, and perceived control. Rather than a deviant behavior, it reflects an adaptive but precarious strategy for managing insecurity and achieving recognition during a critical developmental stage.
Finding Compromise Solutions for Fully Fuzzy Multi-Objective Linear Programming Problems by Using Game Theory Approach
(IOS Press, 2022) Temelcan, Gizem; Kocken, Hale Gonce; Albayrak, Inci
Solving multi-objective linear programming (MOLP) problems and fully fuzzy multi-objective linear programming (FFMOLP) problems involves the trade-off process among several objectives. A new algorithm extended where FFMOLP problems are solved using a 2-player zero-sum game approach to deal with this case. Firstly, The FFMOLP problem is separated into a certain number of fully fuzzy linear programming (FFLP) problems and each is solved by applying any method. After forming a ratio matrix, a game theory approach is applied for finding the weights of objective functions and a weighted LP problem is constructed by these weights. Solving the weighted LP problem, a fuzzy compromise solution of the FFMOLP problem is found. Constructing different ratio matrices, it is also possible to obtain more than one compromise solution to be offered to the decision-maker(s). Some examples are given to show the applicability of the algorithm.
Future of European Security Policies: Is Geopolitical Europe Possible
(Ankara Univ European Union Research Centre, 2024) Ustun, Cigdem; Han, Ahmet K.
Since the aftermath of World War II, the pursuit of European autonomy in ensuring its security has been a constant topic on the European agenda, however never fully realized. The Lisbon Treaty facilitated Union representation as a legal entity and introduced Permanent Structured Cooperation (PESCO) to deepen defense ties. Geopolitical ambitions increased with von Der Leyen's 2019 call for a Geopolitical Commission, preceding the Russia-Ukraine war. Global geopolitical shifts amplify the need for a robust European role. However, the EU's historical struggle in forging a strong security policy fuels skepticism. This study assesses the EU's foreign policy in the Mediterranean and Black Sea amidst regional turmoil, employing a neo-classical realist lens and a global perspective.
Gender Equality and Femvertising Practices in Advertisements
(Mehmet Akif Ersoy University, 2025) Yaman, Duygu; Songur, Ahmet
Female figures, frequently featured as the central element in product and service advertisements, are pivotal in shaping marketing messages. In the broader context of gender representation, the roles attributed to women, both traditional and modern, have undergone significant transformations in contemporary society. Feminism, as a key factor influencing modern role distribution, has led to the emergence of feminist marketing, which is often referred to in the literature as femvertising. Using a content analysis methodology, this study examines commercials, awarded across various categories by the EFFIE organisation in 2022. The goal is to explore whether the feminist marketing in these advertisements is driven by commercial interests or is aimed at empowering the female figure from a societal perspective. A comparative analysis was conducted between the commercials of the same brands on March 8th, International Women's Day. The content analysis revealed that, while the awarded commercials predominantly emphasise traditional gender roles, the commercials for International Women's Day focus more on modern role distribution. Additionally, while femvertising appears less frequently in the International Women's Day commercials, it is more prevalent in the other award-winning ads. To broaden the scope of the research, semi-structured interviews were conducted with brands operating in Istanbul, which had received awards in the Mediacat 2022 Best Advertising Agencies category and were also included in the content analysis sample. The interviews were handled within the framework of a descriptive phenomenological approach. Semi-structured interviews were analysed through the MAXQDA program. They noted that the reason for the increase in femvertising application was that the brand's purpose was to create sympathy in the consumer and to make commercial profit. They stated that femvertising applications were advertising tactics. Another result of the study is that the concept of femvertising is perceived conceptually differently by advertisers and advertising agencies.
The Intolerance of Uncertainty Scale for Children: Reliability, Validity and Adaptation Study
(Klinik Psikiyatri dergisi, 2024) Erden, Gulsen; Celik, Cihat
Objective: The aim of this study is to adapt the Intolerance of Uncertainty Scale for Children (IUSC) into Turkish. Method: The sample of the study consists of 282 children aged 7-12 (M= 9.55, SD = 1.81) and their parents (M= 36.84, SD = 7.04). The Uncertainty Intolerance Scale (IUSC) for Children-Parent Form and Spence Anxiety Scale for Children-Parent (SASC-P) Form were used. The Cronbach Alpha internal consistency and two half test reliability coefficients were calculated for the reliability of the IUSC. Confirmatory Factor Analysis (CFA) was conducted for construct validity and the relationships between the IUSC and the SASC-Parent Form for content validity were evaluated. Results: The CFA analyzes revealed that the 12-item short form of the IUSC had good fit values, and one-factor and two-factor structure were confirmed. As a result of the analyzes significant correlations were found between the total score of the child and parent forms of IUSC-12 and the sub-factors of the SASC-P form, separation anxiety, panic attack, social phobia, obsessive compulsive disorder and agoraphobia scores (child form respectively, r = .25, r = .37, r = .40, r = .25, r = .25; p < .001; parent form respectively, r = .26 , r = .32, r = .43, r = .31, r = .22; p < .001). The reliability analyzes revealed that Cronbach Alpha coefficient for the child form of the IUSC-12 short form was .91 and for the parent form .91. The two half-test Spearman-Brown correlation coefficients were found to be r = .89 for the child form and r = .90 for the parent. Discussion: The results show that parent and child form of the IUSC-12 short form provide reliable and valid results in evaluating the intolerance of uncertainty levels of children in Turkey.
New Generation University: A Model Proposal
(Deomed Publ, Istanbul, 2021) Toprak, Metin; Bayraktar, Yuksel; Erdogan, Armagan; Kolat, Deniz; Sengul, Mehmet
In the last quarter century, since the university is the main source of the human resources required by the knowledge society, structural and functional restructuring efforts of the university institution have been increasing to strengthen the positive impact on economic growth and social development through education and research activities. Today, the Anglo-Saxon and the Far East countries have the most successful university examples in this context; European universities come second in performance, although there are tremendous differences among member countries. Being a candidate for the European Union membership and as a member of the Council of Europe as the first signatory states of the Cultural Convention; implementation of reforms in the European Higher Education Area is obligatory for Turkey. In this study, an organizational and operating model has been developed in line with the European university reform agenda. CoHE's university approach which focuses on thematic and regional development has also been taken into consideration. Five innovations can be mentioned in terms of organizational and functional configuration of the model: (i) Profile of graduate and mission of the new generation university in the fields of education, research and community services, (ii) Policy development and implementation offices, (iii) University ecosystem consultation and steering committee and other committees and boards, (iv) Concept courses and branded courses, (v) Recognition of prior learning, (vi) Coop-education and solution partnerships.
Normalization of Masseter VEMP and Comparison with Cervical VEMP in Normal Individuals
(Springer, 2023) Kilinc, Ezgi; Gencturk, Ertugrul; Tasci, Betul; Serbetcioglu, Mustafa Bulent
ObjectiveThe objective of this study is to obtain normative data of the masseter vestibular-evoked myogenic potential (mVEMP) test in healthy individuals without hearing loss and dizziness and to compare the responses with the cVEMP test.MethodsTwenty healthy individuals (10 males and 10 females) aged 20-30 years without auditory and vestibular disorders participated in the study. First, mVEMP and then cVEMP tests were applied to the individuals who voluntarily participated in the study.ResultsLatency values of the air-conducted mVEMP were 15.90 +/- 1.68 ms for P1 and 25.86 +/- 1.48 ms for N1 and 9.96 +/- 1.50 ms for interpeak latencies. P1N1 amplitude value was 97.89 +/- 37.34 mu V and asymmetry ratio (AR) was 0.13 +/- 0.07. The normative data for the mVEMP threshold was found 84 dB nHL. According to the gender difference in mVEMP measurement parameters, the P1 latency of women was found shorter than the P1 latency of men at all stimulus intensities except 90 dB nHL. There was no statistically significant difference between mVEMP and cVEMP test results in all other severity and all parameters except P1 latency at 100 dB and interpeak latency at 100 dB (p > 0.05).ConclusionIn conclusion, it was the study findings suggest that obtaining normative data on mVEMP could be used as an auxiliary test in the evaluation of the vestibular and trigeminal pathway and the evaluation of patients with various peripheral and central vestibular disorders.
De Novo Malignancy Development Following Kidney Transplantation: Managing Risks and Outcomes in Clinical Practice
(Galenos Publ House, 2025) Huseynov, Amil; Cicek, Sevim Nuran Kuslu
Objective: Denovo malignancy is a significant complication following kidney transplantation, attributed to prolonged immunosuppression.This study evaluates the incidence, risk factors, and clinical outcomes of denovo malignancies in kidney transplant recipients. Material and Methods: A retrospective cohort analysis was conducted on 1200 kidney transplant recipients between 2016 and 2023. Patients were categorized based on the presence or absence of de novo malignancies. Statistical analyses were performed to identify risk factors, including age, sex, comorbidities, and immunosuppressive regimens. Patient and graft survival were assessed using Kaplan-Meier analysis and the log-rank test. Results: Among the study population, 43 patients (3.6%) developed de novo malignancies. The most frequent malignancy types were non-melanoma skin cancers (27.9%) and post-transplant lymphoproliferative disorders (18.6%). Patients with malignancies exhibited a lower three-year survival rate (83.7%) compared to those without malignancies (91.4%), though the difference was not statistically significant (p=0.067). Graft survival at three years was slightly lower in the malignancy group (84.0% vs. 88.7%, p=0.146). Older recipient age was identified as a significant risk factor (hazard ratio=1.03 per year, p=0.025). Conclusion: De novo malignancy remains a concern in kidney transplant recipients, particularly among older patients. Regular screening protocols, lifestyle interventions, and individualized immunosuppressive regimens are essential to mitigate risk and improve outcomes.
The Profit Rate-Interest Rate Nexus Evidence from Machine Learning Algorithms
(Research Center Islamic Economics-IKAM, 2022) Yesilyaprak, Mehmet; Polat, Ali; Ozgur, Onder; Sahal, Suleyman
The main purpose of this study is to examine potential predictors of profit rates and dee posit rates and to examine whether these rates are affected by identical factors. This paper empirically addresses tree based machine learning algorithms (e.g., boosting, bagging, random forest). The empirical findings of the study demonstrate participation banks' profit rates to be more influenced by industrial production due to these banks being in contact more with real economic activity. As expected, however, domestic and global interest rates appear to have great significance in how deposit banks set their rates. This study contributes to the literature in two ways. First, it determines the potential predictors of profit rates and deposit rates in a data-rich environment. Second, the study uses random forest, bagging, and boosting algorithms as methodological tools and benefits from the apparent advantages these algorithms have empirically.
Regenerative Therapy Approaches and Encountered Problems in Sensorineural Hearing Loss
(Bentham Science Publ Ltd, 2023) Kelleci, Kuebra; Golebetmaz, Eda
Hearing loss is one of the most important public health matters worldwide, severely affecting people's social, psychological, and cognitive development. The perception of sound, movement, and balance in vertebrates depends on a special sensory organ called the cochlea, which contains hair cells and supporting cells in the inner ear. Genetic factors, epigenetics, the use of ototoxic drugs (some antibiotics and chemotherapeutics), noise, infections, or even aging can cause loss of hair cells and their related primary neurons, leading to sensorineural hearing loss. Although a sensorineural hearing loss, also known as permanent hearing loss, is treated with hearing aids and cochlear implants, treatment methods are limited. Since even the best implant cannot exhibit the characteristics of the original ear, the permanent sensory deficit will be permanent. For this reason, it has become important to develop regenerative treatment methods to regenerate and replace lost or damaged hair cells and neurons. Developments in stem cell technology have led to promising studies in regenerating damaged/lost hair cells or neurons with endogenous or exogenous cell-based therapies. Epigenetic mechanisms can turn hearing-related genes on and off and determine which proteins to copy. In addition, due to gene silencing, gene replacement, and CRISPR/CAS9 technology, gene therapy methods have accelerated, and studies have been carried out to treat dominant and recessive mutations that cause genetic-induced hearing loss or increase hair cell regeneration. In this paper, potential gene therapy and stem cell applications in the acquisition of cochlear function, which causes sensorineural hearing loss, and the difficulties encountered in these applications are compiled from a bioengineering perspective.

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